SLC7A6OS

Across TCGA cell cohorts, SLC7A6OS mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SLC7A6OS-associated genes across cancer lineages are OR12D3, TOPAZ1, and ARGFX. Each is linked with SLC7A6OS in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC7A6OS-to-partner and partner-to-SLC7A6OS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR12D3 grouped by SLC7A6OS-low versus SLC7A6OS-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A6OS→partner) and Y-score (partner→SLC7A6OS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR12D3 →	+0.056	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	TOPAZ1 →	+0.013	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	ARGFX →	+0.032	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	TMEM207 →	+0.095	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	CXorf51A →	+0.055	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

OR12D3 by SLC7A6OS expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →