SLC7A10

Across TCGA patient cohorts, SLC7A10 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC7A10-associated genes across cancer lineages are Caspase-7-cleavedD198, ERK2, and JNK2. Each is linked with SLC7A10 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC7A10-to-partner and partner-to-SLC7A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by SLC7A10-low versus SLC7A10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A10→partner) and Y-score (partner→SLC7A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.564	+2.189	.018	.034	3	3
UCEC	ERK2 →	+0.170	+2.321	.028	.033	3	2
UCEC	JNK2 →	+0.274	+1.906	<.001	.016	3	2
UCEC	MEK1 →	+0.328	+2.459	.025	.019	3	2
UCEC	TFRC →	+0.620	+3.584	.003	.002	2	3
UCEC	Caspase-8 →	-0.276	-3.087	.006	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Caspase-7-cleavedD198 by SLC7A10 expression — UCEC

Explore this box plot interactively →