SLC7A10

Across TCGA pan-cancer cohorts, SLC7A10 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of SLC7A10’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SLC7A10 RNA is repressed in tumor relative to normal tissue. In most cancer types SLC7A10 is over-expressed in tumor, although a few such as KIRC and BRCA show the opposite, repressed pattern.

KIRC, BRCA, and LUAD are the cancer types where SLC7A10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC7A10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	−0.474	<.001	11	view →
BRCA	All	All	−2.898	<.001	8	view →
LUAD	All	All	+0.850	<.001	8	view →
KIRP	Male	II,III,IV	−0.517	<.001	8	view →
HNSC	All	All	−0.206	.005	8	view →
KICH	All	All	−0.755	<.001	7	view →
THCA	All	II,III,IV	−0.340	.001	7	view →
LIHC	All	All	+0.260	.015	4	view →
UCEC	All	All	+0.278	.019	2	view →
CHOL	All	All	+0.165	.035	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

SLC7A10–KIRC

Open the KIRC breakdown →