SLC7A10

Across TCGA pan-cancer cohorts, SLC7A10 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated SLC7A10 data layer compared with 3 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SLC7A10 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SLC7A10 expression acts as an unfavorable survival marker, although some lineages such as KICH and LUAD show a favorable association.

UCEC, CESC, and BLCA are the cancer types where SLC7A10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	0.605	0.735	<.001	108	view →
CESC	DFS	Quartile	All	0.732	0.876	.001	98	view →
BLCA	DFS	Quartile	All	0.258	0.489	.001	51	view →
KICH	DFS	Median	All	0.974	0.685	.001	51	view →
LUAD	DFS	Tertile	All	0.875	0.717	.002	42	view →
THCA	DFS	Median	IV	0.971	0.764	.007	16	view →
OV	OS	Median	III,IV	0.789	0.879	.001	16	view →
SKCM	DFS	Tertile	IV	0.073	0.954	.004	16	view →
PAAD	OS	Tertile	All	0.515	0.319	.016	15	view →
STAD	DFS	Quartile	All	0.224	0.478	.013	15	view →
UCS	OS	Tertile	IV	0.352	1.000	.036	12	view →
BRCA	OS	Tertile	III,IV	0.723	0.527	.014	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

SLC7A10–UCEC (OS)

Open the UCEC breakdown →