SLC7A10

Across TCGA cell cohorts, SLC7A10 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,368 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SLC7A10-associated GO terms across cancer lineages are Regulation of termination of RNA polymerase II transcription, Regulation of termination of DNA-templated transcription, and Positive regulation of protein localization to nucleus. Each is linked with SLC7A10 in more than 6 cancer types. Because this analysis shows association rather than direction, both SLC7A10-to-partner and partner-to-SLC7A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of termination of RNA polymerase II transcription grouped by SLC7A10-low versus SLC7A10-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A10→partner) and Y-score (partner→SLC7A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of termination of RNA polymerase II transcription →	+0.089	+0.953	.001	.003	3	7
BONE	Regulation of termination of DNA-templated transcription →	+0.089	+0.953	.001	.003	3	7
LUNG_NSCLC_LUAD	Positive regulation of protein localization to nucleus →	+0.061	+0.241	<.001	.004	3	6
BONE	Regulation of heart rate →	-0.075	-1.538	.005	.004	2	7
OVARY	Regulation of base-excision repair →	+0.067	+0.393	<.001	.006	3	6
BONE	Regulation of blood circulation →	-0.053	-1.252	<.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,368 associations by consensus.

Regulation of termination of RNA polymerase II transcription by SLC7A10 expression — BONE

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