SLC7A10

Across TCGA cell cohorts, SLC7A10 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC7A10-associated genes across cancer lineages are NPFFR1, DRGX, and TCP11X2. Each is linked with SLC7A10 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC7A10-to-partner and partner-to-SLC7A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NPFFR1 grouped by SLC7A10-low versus SLC7A10-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC7A10→partner) and Y-score (partner→SLC7A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	NPFFR1 →	+0.015	+4.037	<.001	.004	3	1
BLOOD_Leukemia	DRGX →	+0.279	+3.855	<.001	.007	3	1
BLOOD_Leukemia	TCP11X2 →	+0.200	+4.060	<.001	.003	3	1
LARGE_INTESTINE	CDH20 →	+0.157	+3.766	<.001	.004	3	1
LARGE_INTESTINE	C6orf118 →	+0.154	+4.115	<.001	.001	3	1
LARGE_INTESTINE	SSMEM1 →	+0.030	+4.029	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

NPFFR1 by SLC7A10 expression — BLOOD_Leukemia

Explore this box plot interactively →