SLC6A20

Across TCGA patient cohorts, SLC6A20 mutation is significantly associated with the RNA expression of many other genes, with 3,704 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC6A20-associated genes across cancer lineages are SNORA3C, PPP1R2P6, and GABRE. Each is linked with SLC6A20 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC6A20-to-partner and partner-to-SLC6A20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORA3C grouped by SLC6A20-low versus SLC6A20-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A20→partner) and Y-score (partner→SLC6A20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	SNORA3C →	+0.441	+5.196	<.001	.001	3	2
SKCM	PPP1R2P6 →	+0.082	+2.011	.002	.001	3	2
UCEC	GABRE →	-0.602	-2.654	.003	<.001	3	2
UCEC	FZR1 →	+0.369	+2.069	<.001	<.001	3	2
UCEC	OGDH →	+0.357	+2.542	.002	<.001	3	2
UCEC	MDFI →	-1.288	-2.048	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,704 associations by consensus.

SNORA3C by SLC6A20 expression — CESC

Explore this box plot interactively →