SLC6A11

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC6A11 protein abundance is significantly associated with the RNA expression of many other genes, with 4,069 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLC6A11-associated genes across cancer lineages are SCNN1A, TP53AIP1, and STON2. Each is linked with SLC6A11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC6A11-to-partner and partner-to-SLC6A11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC6A11 versus SCNN1A in HNSC, with a Pearson correlation of -0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC6A11→partner) and Y-score (partner→SLC6A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCSCNN1A →-2.695-2.058<.001.00432
HNSCTP53AIP1 →+1.620+1.799.001<.00132
HNSCSTON2 →+1.151+1.472<.001.00232
GBMPRR13 →-0.482-1.100<.001.00232
HNSCANKRD26P4 →+0.828+1.518.002.00432
HNSCCCDC200 →-0.784-1.795.005.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,069 associations by consensus.

SLC6A11 vs SCNN1A — HNSC

Per-sample scatter of SLC6A11 vs SCNN1A in HNSC (Pearson r = -0.64).

Explore this scatter interactively →

Exploration