SLC5A8

Across TCGA cell cohorts, SLC5A8 RNA expression is significantly associated with the mutation status of many other genes, with 306 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC5A8-associated genes across cancer lineages are LRBA, PLA2R1, and MRGPRD. Each is linked with SLC5A8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC5A8-to-partner and partner-to-SLC5A8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LRBA grouped by SLC5A8-low versus SLC5A8-high in URINARY_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A8→partner) and Y-score (partner→SLC5A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	LRBA →	+3.044	+0.004	.004	<.001	3	2
OESOPHAGUS	PLA2R1 →	+4.906	+0.070	.006	<.001	3	2
OESOPHAGUS	MRGPRD →	+4.906	+0.070	.006	<.001	3	2
BLOOD_Leukemia	RSPO3 →	+5.201	+0.182	.006	<.001	3	2
BLOOD_Leukemia	BAZ2A →	+3.201	+0.061	.005	<.001	3	2
BLOOD_Leukemia	MROH2B →	+3.464	+0.073	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 306 associations by consensus.

LRBA by SLC5A8 expression — URINARY_TRACT

Explore this box plot interactively →