SLC5A6

Across TCGA patient cohorts, SLC5A6 mutation is significantly associated with the RNA expression of many other genes, with 1,287 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC5A6-associated genes across cancer lineages are COX18, AKIP1, and SPR. Each is linked with SLC5A6 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC5A6-to-partner and partner-to-SLC5A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COX18 grouped by SLC5A6-low versus SLC5A6-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A6→partner) and Y-score (partner→SLC5A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	COX18 →	+0.475	+3.371	.002	.004	3	3
UCEC	AKIP1 →	+0.610	+3.711	<.001	<.001	3	3
UCEC	SPR →	+0.719	+3.470	<.001	.002	3	3
UCEC	EIF2S1 →	+0.549	+3.032	.003	<.001	3	3
UCEC	CCT7 →	+0.443	+2.343	.003	.003	3	3
STAD	ALG10 →	+0.484	+3.270	.006	.008	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,287 associations by consensus.

COX18 by SLC5A6 expression — STAD

Explore this box plot interactively →