SLC5A6

Across TCGA cell cohorts, SLC5A6 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,945 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SLC5A6-associated GO terms across cancer lineages are Nucleolar large rRNA transcription by RNA polymerase I, DNA replication initiation, and Biotin transport. Each is linked with SLC5A6 in more than 15 cancer types. Because this analysis shows association rather than direction, both SLC5A6-to-partner and partner-to-SLC5A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleolar large rRNA transcription by RNA polymerase I grouped by SLC5A6-low versus SLC5A6-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A6→partner) and Y-score (partner→SLC5A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Nucleolar large rRNA transcription by RNA polymerase I →	+0.142	+1.039	<.001	<.001	3	16
SOFT_TISSUE	DNA replication initiation →	+0.170	+1.349	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Biotin transport →	+0.336	+1.184	.001	<.001	3	16
BONE	Ribosomal large subunit assembly →	+0.200	+2.348	<.001	<.001	3	15
LIVER	Mitochondrial mRNA polyadenylation →	+0.144	+1.295	<.001	<.001	3	15
LIVER	IMP biosynthetic process →	+0.165	+1.422	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,945 associations by consensus.

Nucleolar large rRNA transcription by RNA polymerase I by SLC5A6 expression — LUNG_SCLC

Explore this box plot interactively →