SLC5A2

Across TCGA cell cohorts, SLC5A2 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC5A2-associated genes across cancer lineages are CENPVL3, CLRN1, and FAM47C. Each is linked with SLC5A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC5A2-to-partner and partner-to-SLC5A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENPVL3 grouped by SLC5A2-low versus SLC5A2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC5A2→partner) and Y-score (partner→SLC5A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CENPVL3 →	+0.209	+2.657	<.001	.007	3	2
PANCREAS	CLRN1 →	+0.020	+4.491	<.001	.003	3	1
SOFT_TISSUE	FAM47C →	+0.006	+5.369	.009	.004	3	1
LARGE_INTESTINE	PTH2R →	+1.151	+2.716	<.001	.009	3	1
LARGE_INTESTINE	GRM1 →	+0.040	+3.750	<.001	.007	3	1
LARGE_INTESTINE	CX3CR1 →	+0.197	+3.252	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

CENPVL3 by SLC5A2 expression — LARGE_INTESTINE

Explore this box plot interactively →