SLC51A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC51A mutation is significantly associated with the RNA expression of many other genes, with 2,266 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC51A-associated genes across cancer lineages are RNY4P14, TEX36-AS1, and IGHVII-65-1. Each is linked with SLC51A in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC51A-to-partner and partner-to-SLC51A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNY4P14 grouped by SLC51A-low versus SLC51A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC51A→partner) and Y-score (partner→SLC51A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRNY4P14 →+0.320+3.625<.001.00433
SKCMTEX36-AS1 →+0.029+4.039<.001.00932
COADIGHVII-65-1 →+0.205+5.824<.001.00132
BRCAMTCO1P49 →+0.075+5.020<.001.00932
UCECVPS26B →+0.467+3.491<.001.00232
UCECDAPK3 →+0.410+3.119.008<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,266 associations by consensus.

RNY4P14 by SLC51A expression — SKCM

Box plot of RNY4P14 in SLC51A-low vs SLC51A-high samples in SKCM.

Explore this box plot interactively →

Exploration