Q-omics provides the consensus-scored IGHVII-65-1 profile across patient tissues and cancer cell-line models. IGHVII-65-1 expression is associated with patient survival in 7 of 34 cancer types, with the highest sampling consensus in KIRC. Additionally, IGHVII-65-1 RNA expression shows 3,042 significant gene co-expression associations, with the highest sampling consensus in UCEC. Together, these results highlight KIRC, and UCEC as cancer lineages where IGHVII-65-1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes IGHVII-65-1 survival associations across molecular data types. IGHVII-65-1 RNA expression shows survival associations in the most cancer types (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

IGHVII-65-1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	7	KIRC (90)	view →

This table ranks reproducible IGHVII-65-1 RNA expression–survival associations across cancer types. High IGHVII-65-1 expression shows unfavorable associations in KIRC, STAD, COAD, OV, LUAD and PCPG. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .019). Together, the overview and detailed table identify KIRC as the clearest survival context for IGHVII-65-1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.510	0.798	.019	90	view →
STAD	DFS	Tertile	All	0.401	0.644	<.001	84	view →
COAD	OS	Tertile	All	0.168	0.806	.002	36	view →
OV	OS	Tertile	IV	0.028	0.759	.002	36	view →
LUAD	OS	Tertile	II,III,IV	0.260	0.684	.002	27	view →
PCPG	DFS	Tertile	All	0.097	0.817	<.001	18	view →

Pink = unfavorable, green = favorable. all 7 lineages →

IGHVII-65-1-KIRC (DFS)

Kaplan–Meier survival curve for IGHVII-65-1 RNA expression in KIRC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with IGHVII-65-1 in patient tissues and cancer cell lines. In patient samples, IGHVII-65-1 shows the broadest associations at the RNA and protein expression levels, with UCEC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	3,042	UCEC (1175)	view →
Function (RNA)	1,963	STAD (854)	view →