SLC4A9

Across TCGA patient cohorts, SLC4A9 mutation is significantly associated with the RNA expression of many other genes, with 5,019 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC4A9-associated genes across cancer lineages are CASTOR2, AATF, and UHRF1. Each is linked with SLC4A9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC4A9-to-partner and partner-to-SLC4A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CASTOR2 grouped by SLC4A9-low versus SLC4A9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A9→partner) and Y-score (partner→SLC4A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CASTOR2 →	+0.755	+2.354	<.001	<.001	3	2
UCEC	AATF →	+0.301	+2.050	.006	<.001	3	2
UCEC	UHRF1 →	+1.053	+2.332	<.001	<.001	3	2
UCEC	H2AC14 →	+0.615	+1.890	<.001	.001	3	2
PRAD	BNIP3P6 →	+0.638	+7.608	<.001	<.001	3	2
PRAD	RN7SL627P →	+0.187	+5.721	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,019 associations by consensus.

CASTOR2 by SLC4A9 expression — UCEC

Explore this box plot interactively →