SLC4A9

Across TCGA pan-cancer cohorts, SLC4A9 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated SLC4A9 data layer compared with 6 for mutation status.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher SLC4A9 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC4A9 expression acts as an unfavorable survival marker, although some lineages such as KICH and MESO show a favorable association.

LIHC, KICH, and UVM are the cancer types where SLC4A9 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Median	All	0.332	0.514	<.001	72	view →
KICH	OS	Median	II,III,IV	1.000	0.771	<.001	43	view →
UVM	DFS	Median	All	0.603	0.863	.001	43	view →
MESO	OS	Tertile	All	0.502	0.257	<.001	37	view →
ACC	OS	Median	II,III,IV	0.864	0.660	.011	21	view →
COAD	DFS	Quartile	All	0.749	0.894	.008	21	view →
CHOL	DFS	Median	III,IV	0.127	0.647	.006	12	view →
THCA	DFS	Quartile	III,IV	0.830	0.956	.008	9	view →
LUSC	OS	Tertile	II,III,IV	0.815	0.684	.027	7	view →
DLBC	OS	Median	II,III,IV	0.530	1.000	.036	7	view →
BLCA	OS	Tertile	All	0.676	0.489	.037	6	view →
LUAD	OS	Tertile	All	0.874	0.741	.007	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

SLC4A9–LIHC (DFS)

Open the LIHC breakdown →