SLC4A9

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC4A9 mutation is significantly associated with the RNA expression of many other genes, with 89 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC4A9-associated genes across cancer lineages are TGM6, C19orf84, and SCN10A. Each is linked with SLC4A9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC4A9-to-partner and partner-to-SLC4A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TGM6 grouped by SLC4A9-low versus SLC4A9-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A9→partner) and Y-score (partner→SLC4A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTTGM6 →+0.017+3.727<.001.00231
BREASTC19orf84 →+0.073+3.684<.001.00431
OVARYSCN10A →+0.006+5.196<.001.00531
OVARYTEX53 →+0.108+5.196<.001.00531
OVARYOR4D2 →+0.016+5.196<.001.00531
BLOOD_LeukemiaSLC32A1 →+0.574+4.223<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 89 associations by consensus.

TGM6 by SLC4A9 expression — BREAST

Box plot of TGM6 in SLC4A9-low vs SLC4A9-high samples in BREAST.

Explore this box plot interactively →

Exploration