SLC4A1AP

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC4A1AP mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC4A1AP-associated genes across cancer lineages are TFRC, PCNA, and ASNS. Each is linked with SLC4A1AP in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC4A1AP-to-partner and partner-to-SLC4A1AP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by SLC4A1AP-low versus SLC4A1AP-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A1AP→partner) and Y-score (partner→SLC4A1AP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADTFRC →+0.752+2.832.010.03533
UCECPCNA →+0.212+3.321.010.00933
COADASNS →+0.702+2.815.001.03632
COADCaspase-7-cleavedD198 →+1.521+2.815<.001.03632
UCECINPP4B →-0.271-1.807.028.02532
UCECp62 Lck ligand →+0.428+3.710<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

TFRC by SLC4A1AP expression — COAD

Box plot of TFRC in SLC4A1AP-low vs SLC4A1AP-high samples in COAD.

Explore this box plot interactively →

Exploration