SLC4A1AP

Across TCGA pan-cancer cohorts, SLC4A1AP RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated SLC4A1AP data layer compared with 4 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher SLC4A1AP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC4A1AP expression acts as an unfavorable survival marker, although some lineages such as KIRC and LUAD show a favorable association.

BLCA, LIHC, and KIRC are the cancer types where SLC4A1AP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Median	All	0.335	0.628	<.001	106	view →
LIHC	DFS	Tertile	All	0.424	0.616	<.001	80	view →
KIRC	DFS	Median	III,IV	0.782	0.491	<.001	71	view →
ACC	DFS	Median	All	0.273	0.615	<.001	66	view →
MESO	DFS	Quartile	All	0.248	0.450	.003	61	view →
HNSC	DFS	Quartile	III,IV	0.206	0.448	.007	47	view →
UVM	DFS	Quartile	III,IV	0.182	0.806	.002	41	view →
KICH	OS	Median	II,III,IV	0.648	0.958	.006	29	view →
UCEC	DFS	Tertile	All	0.614	0.767	.001	26	view →
LUAD	DFS	Tertile	IV	0.829	0.281	.010	24	view →
KIRP	DFS	Median	II,III,IV	0.324	0.637	.009	19	view →
LUSC	OS	Quartile	All	0.798	0.677	.017	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

SLC4A1AP–BLCA (DFS)

Open the BLCA breakdown →