SLC4A1AP

Across TCGA pan-cancer cohorts, SLC4A1AP RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of SLC4A1AP’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where SLC4A1AP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SLC4A1AP is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

HNSC, BLCA, and LUAD are the cancer types where SLC4A1AP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC4A1AP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	III,IV	+0.842	<.001	12	view →
BLCA	Female	All	+0.602	<.001	11	view →
LUAD	Male	II,III,IV	+0.563	<.001	11	view →
LIHC	Female	II,III,IV	+0.943	<.001	9	view →
STAD	Male	II,III,IV	+0.673	<.001	9	view →
KICH	Female	II,III,IV	−1.507	<.001	8	view →
KIRC	Female	All	+0.367	<.001	8	view →
LUSC	Male	II,III,IV	+0.676	<.001	7	view →
BRCA	All	All	+0.242	<.001	6	view →
CHOL	Female	All	+1.773	<.001	5	view →
THCA	All	All	−0.174	.011	5	view →
COAD	Male	All	+0.277	.005	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

SLC4A1AP–HNSC

Open the HNSC breakdown →