SLC4A1AP

Across TCGA cell cohorts, SLC4A1AP mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SLC4A1AP-associated genes across cancer lineages are CRYBB1, LMX1A, and GIMD1. Each is linked with SLC4A1AP in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC4A1AP-to-partner and partner-to-SLC4A1AP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYBB1 grouped by SLC4A1AP-low versus SLC4A1AP-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC4A1AP→partner) and Y-score (partner→SLC4A1AP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	CRYBB1 →	+0.060	+4.029	<.001	.009	3	1
BLOOD_Leukemia	LMX1A →	+0.159	+4.409	<.001	.005	3	1
BLOOD_Leukemia	GIMD1 →	+0.039	+4.152	<.001	.009	3	1
LARGE_INTESTINE	ACSM6 →	+0.020	+3.584	<.001	.002	3	1
LARGE_INTESTINE	TAFA1 →	+0.206	+3.425	.004	<.001	3	1
LARGE_INTESTINE	CHSY3 →	+0.361	+3.252	.007	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

CRYBB1 by SLC4A1AP expression — OVARY

Explore this box plot interactively →