SLC49A3

Across TCGA patient cohorts, SLC49A3 mutation is significantly associated with the RNA expression of many other genes, with 553 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC49A3-associated genes across cancer lineages are MTND6P17, MIR4672, and MIR4325. Each is linked with SLC49A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC49A3-to-partner and partner-to-SLC49A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND6P17 grouped by SLC49A3-low versus SLC49A3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC49A3→partner) and Y-score (partner→SLC49A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MTND6P17 →	+0.218	+4.736	<.001	.003	3	3
UCEC	MIR4672 →	+0.659	+2.626	<.001	.006	3	2
UCEC	MIR4325 →	+0.308	+4.245	<.001	.006	3	2
UCEC	RN7SL248P →	+0.197	+5.137	<.001	<.001	3	2
UCEC	MIR8053 →	+0.578	+4.359	<.001	<.001	3	2
LUSC	SLC9B1P2 →	+0.154	+3.554	.002	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 553 associations by consensus.

MTND6P17 by SLC49A3 expression — UCEC

Explore this box plot interactively →