SLC46A3

Across TCGA patient cohorts, SLC46A3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,991 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC46A3-associated genes across cancer lineages are EIF2B2, TLR4, and PNN. Each is linked with SLC46A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC46A3-to-partner and partner-to-SLC46A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC46A3 versus EIF2B2 in GBM, with a Pearson correlation of -0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC46A3→partner) and Y-score (partner→SLC46A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EIF2B2 →	-0.537	-0.545	.008	<.001	3	3
GBM	TLR4 →	+2.473	+0.686	.004	.007	3	3
CCRCC	PNN →	-0.468	-0.403	.008	.008	3	2
LSCC	KDM3A →	-1.131	-0.515	<.001	<.001	3	2
GBM	PDE1B →	+1.304	+0.545	.004	<.001	3	2
LSCC	RPS15A →	-0.693	-0.501	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,991 associations by consensus.

SLC46A3 vs EIF2B2 — GBM

Explore this scatter interactively →