SLC44A5

Across TCGA cell cohorts, SLC44A5 mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SLC44A5-associated genes across cancer lineages are FAM47C, OR5M10, and COX4I2. Each is linked with SLC44A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC44A5-to-partner and partner-to-SLC44A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM47C grouped by SLC44A5-low versus SLC44A5-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC44A5→partner) and Y-score (partner→SLC44A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	FAM47C →	+0.006	+2.665	.001	.004	3	2
BLOOD_Lymphoma	OR5M10 →	+0.019	+5.643	<.001	.002	3	2
LUNG_NSCLC_LUAD	COX4I2 →	+0.035	+3.228	<.001	.003	3	1
LUNG_NSCLC_LUAD	XAGE3 →	+0.096	+3.215	<.001	<.001	3	1
LUNG_NSCLC_LUAD	COL6A5 →	+0.035	+2.760	.001	.003	3	1
LUNG_NSCLC_LUAD	DBX2 →	+0.009	+3.273	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

FAM47C by SLC44A5 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →