SLC44A5

Across TCGA pan-cancer cohorts, SLC44A5 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated SLC44A5 data layer compared with 9 for mutation status.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher SLC44A5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SLC44A5 expression acts as an unfavorable survival marker, although some lineages such as UCS and OV show a favorable association.

KIRP, UCS, and LIHC are the cancer types where SLC44A5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	All	0.914	1.000	.002	56	view →
UCS	DFS	Tertile	II,III,IV	0.573	0.187	.006	50	view →
LIHC	DFS	Quartile	All	0.302	0.671	<.001	21	view →
UVM	OS	Quartile	II,III,IV	0.640	0.928	.005	19	view →
OV	OS	Median	All	0.881	0.799	.011	16	view →
KIRC	DFS	Median	All	0.503	0.728	<.001	16	view →
ACC	DFS	Median	II,III,IV	0.153	0.736	.001	13	view →
MESO	DFS	Quartile	All	0.325	0.906	.006	12	view →
LUSC	OS	Quartile	All	0.856	0.593	.009	10	view →
UCEC	DFS	Quartile	All	0.756	0.855	.022	10	view →
STAD	DFS	Quartile	IV	0.409	0.886	.041	9	view →
SARC	DFS	Median	All	0.399	0.566	.020	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

SLC44A5–KIRP (OS)

Open the KIRP breakdown →