SLC39A7

Across TCGA cell cohorts, SLC39A7 mutation is significantly associated with the mutation status of many other genes, with 2,541 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC39A7-associated genes across cancer lineages are HSF2, SLC4A8, and SPHK2. Each is linked with SLC39A7 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC39A7-to-partner and partner-to-SLC39A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSF2 grouped by SLC39A7-low versus SLC39A7-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A7→partner) and Y-score (partner→SLC39A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HSF2 →	+6.321	+6.321	.001	.001	1	3
LARGE_INTESTINE	SLC4A8 →	+2.865	+4.217	.007	.007	1	3
LARGE_INTESTINE	SPHK2 →	+4.672	+5.329	<.001	<.001	1	3
BLOOD_Leukemia	APBB1IP →	+5.321	+5.894	.002	.002	1	3
SKIN	LNPEP →	+4.239	+5.053	.007	.007	1	3
BLOOD_Leukemia	KNG1 →	+4.321	+5.285	.005	.005	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,541 associations by consensus.

HSF2 by SLC39A7 expression — BLOOD_Leukemia

Explore this box plot interactively →