SLC38A6

Across TCGA cell cohorts, SLC38A6 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLC38A6-associated genes across cancer lineages are TBC1D21, KRTAP21-3, and RESP18. Each is linked with SLC38A6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC38A6-to-partner and partner-to-SLC38A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBC1D21 grouped by SLC38A6-low versus SLC38A6-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A6→partner) and Y-score (partner→SLC38A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	TBC1D21 →	+0.076	+4.129	<.001	.007	3	1
STOMACH	KRTAP21-3 →	+0.385	+4.285	<.001	.007	3	1
OVARY	RESP18 →	+0.038	+5.196	<.001	.005	3	1
SKIN	FAM47C →	+0.006	+4.977	<.001	.007	3	1
SKIN	MDFIC2 →	+0.155	+4.977	<.001	.007	3	1
LARGE_INTESTINE	PLCB3 →	+0.732	+3.064	.005	.009	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

TBC1D21 by SLC38A6 expression — STOMACH

Explore this box plot interactively →