SLC38A5

Across TCGA cell cohorts, SLC38A5 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC38A5-associated genes across cancer lineages are OR4S2, C6orf118, and CCDC70. Each is linked with SLC38A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC38A5-to-partner and partner-to-SLC38A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4S2 grouped by SLC38A5-low versus SLC38A5-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC38A5→partner) and Y-score (partner→SLC38A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	OR4S2 →	+0.020	+5.285	<.001	.003	3	1
LARGE_INTESTINE	C6orf118 →	+0.205	+4.115	<.001	.001	3	1
LARGE_INTESTINE	CCDC70 →	+0.035	+3.658	.002	.005	3	1
LARGE_INTESTINE	KLRF1 →	+0.890	+3.554	<.001	.007	3	1
LARGE_INTESTINE	DEFA4 →	+0.026	+4.022	<.001	.006	3	1
LARGE_INTESTINE	AMY1B →	+0.180	+3.196	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

OR4S2 by SLC38A5 expression — STOMACH

Explore this box plot interactively →