SLC36A4

Across TCGA patient cohorts, SLC36A4 mutation is significantly associated with the RNA expression of many other genes, with 3,393 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC36A4-associated genes across cancer lineages are UGT1A12P, TMEM25, and HSPA13. Each is linked with SLC36A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC36A4-to-partner and partner-to-SLC36A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UGT1A12P grouped by SLC36A4-low versus SLC36A4-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC36A4→partner) and Y-score (partner→SLC36A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	UGT1A12P →	+0.181	+5.786	<.001	<.001	3	2
UCEC	TMEM25 →	+0.375	+2.353	.006	.003	3	2
UCEC	HSPA13 →	+0.488	+2.243	.005	.005	3	2
UCEC	MIER3 →	+0.419	+1.949	.006	.001	3	2
UCEC	LAD1 →	-0.912	-1.917	<.001	.001	3	2
UCEC	AMFR →	+0.476	+2.436	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,393 associations by consensus.

UGT1A12P by SLC36A4 expression — CESC

Explore this box plot interactively →