SLC30A7

Across TCGA patient cohorts, SLC30A7 mutation is significantly associated with the RNA expression of many other genes, with 2,256 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC30A7-associated genes across cancer lineages are MIR551B, OR2T12, and H3P46. Each is linked with SLC30A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC30A7-to-partner and partner-to-SLC30A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR551B grouped by SLC30A7-low versus SLC30A7-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC30A7→partner) and Y-score (partner→SLC30A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR551B →	+0.276	+7.731	<.001	.009	3	2
BLCA	OR2T12 →	+0.034	+7.640	.002	.009	3	2
BRCA	H3P46 →	+0.193	+7.731	<.001	.009	3	1
HNSC	VCY →	+0.099	+7.954	<.001	.008	3	1
HNSC	RNU1-15P →	+0.323	+7.954	<.001	.008	3	1
HNSC	SNORD115-29 →	+0.497	+7.954	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,256 associations by consensus.

MIR551B by SLC30A7 expression — BRCA

Explore this box plot interactively →