SLC2A8

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC2A8 mutation is significantly associated with the RNA expression of many other genes, with 323 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC2A8-associated genes across cancer lineages are RNU6-918P, RPL12P5, and MIR6803. Each is linked with SLC2A8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC2A8-to-partner and partner-to-SLC2A8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-918P grouped by SLC2A8-low versus SLC2A8-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC2A8→partner) and Y-score (partner→SLC2A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PRADRNU6-918P →+0.421+5.166<.001.00732
READRPL12P5 →+0.220+5.219<.001.00632
SKCMMIR6803 →+0.417+4.328<.001.00732
COADMTND4P33 →+0.095+4.537<.001.00632
UCECRNU6-1292P →+0.268+3.231<.001.00432
UCECRNU6-879P →+0.431+2.067.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 323 associations by consensus.

RNU6-918P by SLC2A8 expression — PRAD

Box plot of RNU6-918P in SLC2A8-low vs SLC2A8-high samples in PRAD.

Explore this box plot interactively →

Exploration