SLC29A1

Across TCGA patient cohorts, SLC29A1 mutation is significantly associated with the RNA expression of many other genes, with 2,804 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC29A1-associated genes across cancer lineages are MCM10, GNPDA1, and KNSTRN. Each is linked with SLC29A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC29A1-to-partner and partner-to-SLC29A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MCM10 grouped by SLC29A1-low versus SLC29A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC29A1→partner) and Y-score (partner→SLC29A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MCM10 →	+0.633	+2.439	.004	.001	3	3
UCEC	GNPDA1 →	+0.616	+2.392	<.001	<.001	3	3
UCEC	KNSTRN →	+0.554	+2.338	.001	.003	3	3
UCEC	CCNB1 →	+0.701	+2.392	<.001	<.001	3	3
UCEC	MIR6728 →	+0.424	+1.721	.007	.005	3	2
UCEC	SNORD91B →	+0.552	+2.424	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,804 associations by consensus.

MCM10 by SLC29A1 expression — UCEC

Explore this box plot interactively →