SLC29A1

Across TCGA pan-cancer cohorts, SLC29A1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated SLC29A1 data layer compared with 8 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher SLC29A1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated SLC29A1 expression acts as an unfavorable survival marker, although some lineages such as UCS and ACC show a favorable association.

UCS, MESO, and KIRP are the cancer types where SLC29A1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Median	II,III,IV	0.595	0.198	.001	82	view →
MESO	OS	Median	All	0.272	0.500	<.001	66	view →
KIRP	OS	Median	All	0.546	0.946	.001	53	view →
ACC	OS	Median	All	0.791	0.451	<.001	40	view →
LGG	OS	Tertile	All	0.716	0.883	<.001	36	view →
COAD	DFS	Median	IV	0.356	0.606	.002	35	view →
UCEC	OS	Tertile	All	0.879	0.950	.005	28	view →
CESC	DFS	Quartile	All	0.625	0.848	.001	22	view →
LUAD	OS	Median	II,III,IV	0.770	0.646	.004	20	view →
THYM	OS	Median	All	0.960	0.770	.004	19	view →
HNSC	OS	Median	All	0.621	0.795	.002	18	view →
BRCA	DFS	Tertile	All	0.878	0.922	.028	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

SLC29A1–UCS (OS)

Open the UCS breakdown →