SLC26A7

Across TCGA cell cohorts, SLC26A7 mutation is significantly associated with the RNA expression of many other genes, with 575 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC26A7-associated genes across cancer lineages are MT1HL1, FAU, and RCHY1. Each is linked with SLC26A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC26A7-to-partner and partner-to-SLC26A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MT1HL1 grouped by SLC26A7-low versus SLC26A7-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC26A7→partner) and Y-score (partner→SLC26A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MT1HL1 →	+0.419	+4.922	<.001	.009	3	2
LARGE_INTESTINE	FAU →	+0.329	+1.949	<.001	.002	3	2
LARGE_INTESTINE	RCHY1 →	+0.585	+1.949	.004	.002	3	2
BLOOD_Myeloma	MMP26 →	+0.026	+4.807	<.001	.006	3	1
BLOOD_Myeloma	C18orf63 →	+0.013	+4.807	<.001	.006	3	1
CNS	TAS2R39 →	+0.024	+4.981	.004	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 575 associations by consensus.

MT1HL1 by SLC26A7 expression — BLOOD_Leukemia

Explore this box plot interactively →