SLC26A7

Across TCGA pan-cancer cohorts, SLC26A7 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated SLC26A7 data layer compared with 11 for mutation status.

The strongest signal is observed in uveal melanoma (UVM), where higher SLC26A7 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC26A7 expression acts as an unfavorable survival marker, although some lineages such as READ and BLCA show a favorable association.

UVM, READ, and LUAD are the cancer types where SLC26A7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	All	0.379	0.711	.001	85	view →
READ	OS	Median	III,IV	0.683	0.255	<.001	54	view →
LUAD	OS	Tertile	All	0.180	0.439	.001	48	view →
LGG	DFS	Tertile	All	0.659	0.837	<.001	29	view →
UCEC	OS	Quartile	II,III,IV	0.277	0.783	.019	26	view →
KIRP	DFS	Median	All	0.801	0.932	.003	25	view →
LAML	DFS	Median	All	0.437	0.696	.010	18	view →
LIHC	OS	Quartile	All	0.504	0.725	.006	16	view →
BLCA	OS	Tertile	All	0.517	0.325	.004	13	view →
HNSC	DFS	Median	II,III,IV	0.763	0.636	.003	13	view →
MESO	DFS	Median	All	0.223	0.622	.002	12	view →
UCS	DFS	Tertile	IV	0.956	0.381	.024	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

SLC26A7–UVM (DFS)

Open the UVM breakdown →