SLC25A5

Across TCGA patient cohorts, SLC25A5 mutation is significantly associated with the RNA expression of many other genes, with 820 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A5-associated genes across cancer lineages are AKR1B10P2, TERF1P1, and RNU6-1299P. Each is linked with SLC25A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A5-to-partner and partner-to-SLC25A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AKR1B10P2 grouped by SLC25A5-low versus SLC25A5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A5→partner) and Y-score (partner→SLC25A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AKR1B10P2 →	+0.032	+2.773	.004	.004	3	2
CESC	TERF1P1 →	+0.043	+4.760	<.001	.003	3	2
SKCM	RNU6-1299P →	+0.409	+5.594	<.001	.004	3	2
SKCM	RN7SL44P →	+0.165	+5.097	<.001	.008	3	2
SKCM	LINC02283 →	+0.169	+6.469	<.001	.001	3	2
UCEC	LINC00294 →	+0.468	+2.828	.006	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 820 associations by consensus.

AKR1B10P2 by SLC25A5 expression — UCEC

Explore this box plot interactively →