SLC25A5

Across TCGA cell cohorts, SLC25A5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,933 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC25A5-associated GO terms across cancer lineages are DNA replication initiation, snRNA pseudouridine synthesis, and Spindle elongation. Each is linked with SLC25A5 in more than 13 cancer types. Because this analysis shows association rather than direction, both SLC25A5-to-partner and partner-to-SLC25A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by SLC25A5-low versus SLC25A5-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A5→partner) and Y-score (partner→SLC25A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	DNA replication initiation →	+0.159	+0.660	<.001	<.001	3	14
PANCREAS	snRNA pseudouridine synthesis →	+0.072	+0.790	<.001	<.001	3	13
KIDNEY	Spindle elongation →	+0.217	+0.688	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	DNA replication checkpoint signaling →	+0.173	+1.316	<.001	<.001	3	12
KIDNEY	Lagging strand elongation →	+0.136	+0.994	<.001	<.001	3	12
KIDNEY	Cell cycle DNA replication initiation →	+0.177	+0.876	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,933 associations by consensus.

DNA replication initiation by SLC25A5 expression — BLOOD_Myeloma

Explore this box plot interactively →