SLC25A39

Across TCGA patient cohorts, SLC25A39 mutation is significantly associated with the RNA expression of many other genes, with 702 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A39-associated genes across cancer lineages are MIR6803, MIR6839, and MIR4760. Each is linked with SLC25A39 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A39-to-partner and partner-to-SLC25A39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6803 grouped by SLC25A39-low versus SLC25A39-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A39→partner) and Y-score (partner→SLC25A39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6803 →	+0.172	+4.671	<.001	.002	3	2
UCEC	MIR6839 →	+0.183	+2.714	.003	.005	3	2
SKCM	MIR4760 →	+0.193	+5.421	<.001	.001	3	2
CESC	GAPDHP56 →	+0.038	+6.569	<.001	.001	3	2
BRCA	RPL23AP39 →	+0.114	+5.288	<.001	.006	3	2
BRCA	RN7SKP221 →	+0.192	+7.471	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 702 associations by consensus.

MIR6803 by SLC25A39 expression — UCEC

Explore this box plot interactively →