SLC25A39

Across TCGA patient cohorts, SLC25A39 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A39-associated genes across cancer lineages are N-Ras, P-Cadherin, and 14-3-3_beta. Each is linked with SLC25A39 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A39-to-partner and partner-to-SLC25A39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, N-Ras grouped by SLC25A39-low versus SLC25A39-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A39→partner) and Y-score (partner→SLC25A39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	N-Ras →	-0.180	-3.150	.001	.019	3	2
UCEC	P-Cadherin →	-0.175	-2.446	.011	.020	3	2
UCEC	14-3-3_beta →	-0.143	-3.149	.003	.019	3	1
UCEC	A-Raf_pS299 →	-0.124	-2.459	.032	.020	3	1
UCEC	ACC_pS79 →	+0.461	+2.459	.005	.020	3	1
UCEC	GSK-3a-b_pS21_S9 →	+0.534	+2.817	.009	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

N-Ras by SLC25A39 expression — UCEC

Explore this box plot interactively →