SLC25A39

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC25A39 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC25A39-associated genes across cancer lineages are ACSM2A, ELOA3DP, and FAM205A. Each is linked with SLC25A39 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A39-to-partner and partner-to-SLC25A39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACSM2A grouped by SLC25A39-low versus SLC25A39-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A39→partner) and Y-score (partner→SLC25A39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaACSM2A →+0.016+4.807<.001.00631
LARGE_INTESTINEELOA3DP →+0.025+3.688<.001.00231
LARGE_INTESTINEFAM205A →+0.020+3.614<.001.00631
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ACSM2A by SLC25A39 expression — BLOOD_Myeloma

Box plot of ACSM2A in SLC25A39-low vs SLC25A39-high samples in BLOOD_Myeloma.

Explore this box plot interactively →

Exploration