SLC25A39

Across TCGA cell cohorts, SLC25A39 mutation is significantly associated with the mutation status of many other genes, with 2,620 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC25A39-associated genes across cancer lineages are ZNF821, TNPO2, and TANC1. Each is linked with SLC25A39 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC25A39-to-partner and partner-to-SLC25A39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF821 grouped by SLC25A39-low versus SLC25A39-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A39→partner) and Y-score (partner→SLC25A39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ZNF821 →	+4.415	+4.977	.007	.007	1	3
BLOOD_Leukemia	TNPO2 →	+3.894	+5.247	.001	.001	1	3
BLOOD_Leukemia	TANC1 →	+2.779	+4.326	.006	.006	1	3
BLOOD_Leukemia	TRPM4 →	+2.894	+4.432	.005	.005	1	3
BLOOD_Leukemia	CWC22 →	+4.479	+5.635	<.001	<.001	1	3
BLOOD_Leukemia	LARGE2 →	+4.894	+4.894	.004	.004	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,620 associations by consensus.

ZNF821 by SLC25A39 expression — OVARY

Explore this box plot interactively →