SLC25A35

Across TCGA patient cohorts, SLC25A35 protein abundance is significantly associated with the RNA expression of many other genes, with 7,566 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SLC25A35-associated genes across cancer lineages are AFF3, SPAG8, and DNAAF1. Each is linked with SLC25A35 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC25A35-to-partner and partner-to-SLC25A35 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC25A35 versus AFF3 in BRCA, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A35→partner) and Y-score (partner→SLC25A35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AFF3 →	+1.620	+0.585	<.001	<.001	3	4
UCEC	SPAG8 →	+1.092	+0.744	.001	<.001	3	3
UCEC	DNAAF1 →	+1.729	+1.011	<.001	<.001	3	3
BRCA	CFAP70 →	+0.891	+0.588	<.001	<.001	3	3
BRCA	BORCS7 →	+0.765	+0.737	<.001	<.001	3	3
UCEC	TIGD4 →	+0.591	+0.725	.005	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,566 associations by consensus.

SLC25A35 vs AFF3 — BRCA

Explore this scatter interactively →