SLC25A31

Across TCGA cell cohorts, SLC25A31 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC25A31-associated genes across cancer lineages are SPINK9, NAA11, and AGRP. Each is linked with SLC25A31 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A31-to-partner and partner-to-SLC25A31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPINK9 grouped by SLC25A31-low versus SLC25A31-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A31→partner) and Y-score (partner→SLC25A31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SPINK9 →	+0.269	+3.115	<.001	.004	3	2
LARGE_INTESTINE	NAA11 →	+0.302	+3.443	.009	.009	3	1
LARGE_INTESTINE	AGRP →	+0.117	+2.994	<.001	.006	3	1
LARGE_INTESTINE	OR1L6 →	+0.015	+3.700	<.001	.009	3	1
LARGE_INTESTINE	FAM153B →	+0.527	+3.426	<.001	.007	3	1
LARGE_INTESTINE	TAFA1 →	+0.234	+3.103	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

SPINK9 by SLC25A31 expression — LARGE_INTESTINE

Explore this box plot interactively →