SLC25A20

Across TCGA patient cohorts, SLC25A20 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC25A20-associated genes across cancer lineages are ATM, Myosin-IIa_pS1943, and Caspase-8. Each is linked with SLC25A20 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A20-to-partner and partner-to-SLC25A20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by SLC25A20-low versus SLC25A20-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A20→partner) and Y-score (partner→SLC25A20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.798	-3.000	.001	.036	3	2
UCEC	Myosin-IIa_pS1943 →	+0.280	+3.183	.013	.010	3	1
UCEC	Caspase-8 →	-0.302	-3.169	.028	.020	3	1
UCEC	C-Raf →	+0.258	+3.000	.001	.036	3	1
UCEC	AMPK_pT172 →	+0.464	+3.183	.039	.010	2	1
UCEC	Cyclin-B1 →	+0.784	+3.169	.011	.020	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

ATM by SLC25A20 expression — UCEC

Explore this box plot interactively →