SLC25A2

Across TCGA cell cohorts, SLC25A2 mutation is significantly associated with the RNA expression of many other genes, with 278 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC25A2-associated genes across cancer lineages are CCDC110, NUMBL, and CUEDC2. Each is linked with SLC25A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A2-to-partner and partner-to-SLC25A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC110 grouped by SLC25A2-low versus SLC25A2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A2→partner) and Y-score (partner→SLC25A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CCDC110 →	+0.592	+3.440	<.001	.006	3	2
LARGE_INTESTINE	NUMBL →	+0.892	+3.212	.004	.006	3	1
LARGE_INTESTINE	CUEDC2 →	+0.598	+3.212	.004	.006	3	1
LARGE_INTESTINE	TBC1D30 →	+0.955	+3.212	.003	.006	3	1
LARGE_INTESTINE	GPR63 →	+0.976	+3.212	<.001	.006	3	1
LARGE_INTESTINE	HBS1L →	+0.847	+3.212	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 278 associations by consensus.

CCDC110 by SLC25A2 expression — BLOOD_Leukemia

Explore this box plot interactively →