SLC25A15

Across TCGA cell cohorts, SLC25A15 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLC25A15-associated genes across cancer lineages are ACER1, KRT71, and TMCO5A. Each is linked with SLC25A15 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC25A15-to-partner and partner-to-SLC25A15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACER1 grouped by SLC25A15-low versus SLC25A15-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC25A15→partner) and Y-score (partner→SLC25A15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ACER1 →	+0.113	+3.823	<.001	.006	3	1
SKIN	KRT71 →	+0.024	+4.977	.004	.007	3	1
SKIN	TMCO5A →	+0.062	+4.977	.003	.007	3	1
SKIN	SPRR4 →	+0.337	+4.977	<.001	.007	3	1
SKIN	TAS2R60 →	+0.050	+5.415	<.001	.004	3	1
SKIN	SPRR5 →	+0.280	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

ACER1 by SLC25A15 expression — LARGE_INTESTINE

Explore this box plot interactively →