SLC25A15

Across TCGA pan-cancer cohorts, SLC25A15 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of SLC25A15’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SLC25A15 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SLC25A15 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

COAD, THCA, and STAD are the cancer types where SLC25A15 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC25A15 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+1.354	<.001	12	view →
THCA	All	IV	−4.260	<.001	11	view →
STAD	All	II,III,IV	+1.094	<.001	10	view →
BLCA	All	III,IV	+1.079	<.001	10	view →
LUAD	Male	II,III,IV	+1.040	<.001	9	view →
KIRC	Male	II,III,IV	−1.035	<.001	9	view →
HNSC	All	IV	+0.891	<.001	8	view →
LUSC	Male	II,III,IV	+1.086	<.001	6	view →
KIRP	Male	All	−0.989	<.001	6	view →
UCEC	All	All	+0.955	.001	6	view →
BRCA	All	II,III,IV	+0.618	<.001	6	view →
CHOL	All	All	−2.253	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

SLC25A15–COAD

Open the COAD breakdown →