SLC24A1

Across TCGA patient cohorts, SLC24A1 mutation is significantly associated with the RNA expression of many other genes, with 4,238 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC24A1-associated genes across cancer lineages are EMC6, CA14, and MED9. Each is linked with SLC24A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC24A1-to-partner and partner-to-SLC24A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EMC6 grouped by SLC24A1-low versus SLC24A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC24A1→partner) and Y-score (partner→SLC24A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EMC6 →	+0.575	+2.459	<.001	<.001	3	4
UCEC	CA14 →	+0.410	+2.303	.008	<.001	3	3
COAD	MED9 →	+0.420	+3.389	<.001	.004	3	3
UCEC	CHAF1A →	+0.655	+2.343	<.001	<.001	3	3
UCEC	CENPM →	+0.587	+2.632	<.001	<.001	3	3
UCEC	FBXO7 →	+0.394	+1.828	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,238 associations by consensus.

EMC6 by SLC24A1 expression — UCEC

Explore this box plot interactively →