SLC24A1

Across TCGA patient cohorts, SLC24A1 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC24A1-associated genes across cancer lineages are Cyclin-B1, eEF2, and STAT3_pY705. Each is linked with SLC24A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC24A1-to-partner and partner-to-SLC24A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by SLC24A1-low versus SLC24A1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC24A1→partner) and Y-score (partner→SLC24A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Cyclin-B1 →	+0.661	+3.012	.004	.018	3	3
COAD	eEF2 →	+0.352	+3.178	.015	.010	3	2
UCEC	STAT3_pY705 →	-0.365	-2.000	<.001	.002	3	2
UCEC	Caspase-8 →	-0.313	-2.378	<.001	<.001	3	2
UCEC	A-Raf_pS299 →	-0.096	-1.874	.011	.049	3	2
UCEC	ERK2 →	+0.201	+1.777	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Cyclin-B1 by SLC24A1 expression — SKCM

Explore this box plot interactively →