SLC24A1

Across TCGA cell cohorts, SLC24A1 mutation is significantly associated with the RNA expression of many other genes, with 349 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC24A1-associated genes across cancer lineages are ADIG, ADAM7, and OR4F4. Each is linked with SLC24A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC24A1-to-partner and partner-to-SLC24A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADIG grouped by SLC24A1-low versus SLC24A1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC24A1→partner) and Y-score (partner→SLC24A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ADIG →	+0.015	+4.569	<.001	.003	3	2
LARGE_INTESTINE	ADAM7 →	+0.003	+2.760	<.001	.003	3	2
BLOOD_Lymphoma	OR4F4 →	+0.019	+5.169	<.001	.001	3	1
BLOOD_Lymphoma	CXorf51A →	+0.178	+5.452	<.001	<.001	3	1
BLOOD_Lymphoma	ERVV-2 →	+0.043	+4.927	.001	.001	3	1
LUNG_NSCLC_LUAD	UTF1 →	+0.523	+4.371	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 349 associations by consensus.

ADIG by SLC24A1 expression — BLOOD_Leukemia

Explore this box plot interactively →